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Freezing of Gait in Parkinsonism and its Potential Drug Treatment

[ Vol. 14 , Issue. 4 ]

Author(s):

Li-Li Zhang, S. Duff Canning and Xiao-Ping Wang   Pages 302 - 306 ( 5 )

Abstract:


Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.

Keywords:

Drug treatment, freezing of gait, Levodopa, Parkinson’s disease, Parkinsonism.

Affiliation:

Department of Neurology, Shanghai First People’s Hospital, Shanghai Jiao-Tong University, China. 200080.

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