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Freezing of Gait in Parkinsonism and its Potential Drug Treatment

[ Vol. 14 , Issue. 4 ]


Li-Li Zhang, S. Duff Canning and Xiao-Ping Wang   Pages 302 - 306 ( 5 )


Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.


Drug treatment, freezing of gait, Levodopa, Parkinson’s disease, Parkinsonism.


Department of Neurology, Shanghai First People’s Hospital, Shanghai Jiao-Tong University, China. 200080.

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